Coughlin has nine lives - he's not going anywhere.
Trestman, well, that would be just like the Bears. Things aren't great this year, but it's not all on him, and it hasn't been a tire fire. He needs more time to show if he can get it right. Of course, if things continue to go bad, I'm all for him sticking around then too!
Ryan IS a tire fire. I'd say he's entering Matt Millen territory, but he could well succeed as DC - just get him out of that top job.
Who knows with Harbaugh. Did anyone see him and Kaepernick during the warmup before the Seahawks game? He was pounding on the QB's pad, then Kap did the same back to him and I couldn't decide if it was part of the pumping each other up, or if he was enjoying hammering his coach.
Smith? I'm sure I don't know. He seems to be without personality. Seems like that team should be ok, but it sure isn't.