There is so much that is LUCK and making a Draft Pick. The picks below were certainly productive game changers for their teams:
12 Baltimore Ravens Haloti Ngata DT Oregon
14 Philadelphia Eagles Brodrick Bunkley DT Florida State
17 Minnesota Vikings Chad Greenway LB Iowa
20 Kansas City Chiefs Tamba Hali DE Penn State
I didn't look past the 2oth Pick; that wasn't a good Draft overall as I recall it.