Until last year, under McCarthy it did seem to take the Packers offensive line some time to gel. However, last year the Packers scored 28, 38 and 30 points in their 1st 3 games, with 2 of those against good defenses. They struggled running the ball against SF, but ran it very well against Washington and Cincy. So I have some hope that the offense will not be dysfunctional.
I still have no clue who will win though.