The Eagles can't really do anything unless Vick plays out of his mind and the Eagles jump out to a big lead. That defense just can't line up in base and stop people. They have their DEs lined up crazy-wide to rush the passer, but they have neither the DTs nor the LBs to make that work against the run, and they have good CBs but they just don't have safeties to hold up in pass defense unless pressure gets there.
The Eagles script is pretty much "Jump out to a big lead because Vick plays awesome, and then play nickel and rush the passer" I don't think things turn out well insofar as they deviate from that script.