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  • Originally posted by mraynrand View Post
    kinda sorta. Tell me what's in those exosome/vesicles that regrows cartilage in a few hours. lol.
    Nothing. However there is something that eliminated inflation body wide within a few hours. And over the course of weeks the cartilage repaired.

    This is the new science of medicine. Using our bodies own defenses to fix it.

    Immunotherapy in cancer is changing the world.
    The only time success comes before work is in the dictionary -- Vince Lombardi

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    • Originally posted by bobblehead View Post
      Nothing. However there is something that eliminated inflation body wide within a few hours. And over the course of weeks the cartilage repaired.

      This is the new science of medicine. Using our bodies own defenses to fix it.

      Immunotherapy in cancer is changing the world.
      I wouldn’t put non-specific stem cell therapies in the same category as immunotherapy for cancer.

      It’s far more likely that simply controlling inflammation and the inflammatory response was the key Graham needed for what should be natural repair of the tendon.

      But I confess I haven’t read a lot of this literature.
      "Never, never ever support a punk like mraynrand. Rather be as I am and feel real sympathy for his sickness." - Woodbuck

      Comment


      • Originally posted by bobblehead View Post
        Nothing. However there is something that eliminated inflation body wide within a few hours. And over the course of weeks the cartilage repaired.

        This is the new science of medicine. Using our bodies own defenses to fix it.

        Immunotherapy in cancer is changing the world.
        So if he was on a anti-inflammation protocol and it worked, then the vesicles contributed what exactly?
        Bud Adams told me the franchise he admired the most was the Kansas City Chiefs. Then he asked for more hookers and blow.

        Comment


        • Originally posted by pbmax View Post
          So if he was on a anti-inflammation protocol and it worked, then the vesicles contributed what exactly?
          Some mesenchymal stem cells or their vesicles can produce factors that in duce chondrocyte markers (possibly help repair) and suppress the expression of things that break down (or remodel) cartilage, as well as suppress inflammation and protect the resident cells that normally effect repairs from cellular death. I saw some osteoarthritis models that showed some promising results. I did see that they treated the cells with TGF beta - that kind of direct therapy has been under investigation for a while. So they are stimulating these cells in culture, then injecting them in or injecting their exosome/vesicles into various joints to see if they get repair or suppress osteoarthritis (mouse model). Seems somewhat promising for stimulating repair process or delaying some osteoarthritis effects. Still seems somewhat non-specific, but might help people showing slow normal recovery.

          OK, back to work...
          "Never, never ever support a punk like mraynrand. Rather be as I am and feel real sympathy for his sickness." - Woodbuck

          Comment


          • Originally posted by mraynrand View Post
            Some mesenchymal stem cells or their vesicles can produce factors that in duce chondrocyte markers (possibly help repair) and suppress the expression of things that break down (or remodel) cartilage, as well as suppress inflammation and protect the resident cells that normally effect repairs from cellular death. I saw some osteoarthritis models that showed some promising results. I did see that they treated the cells with TGF beta - that kind of direct therapy has been under investigation for a while. So they are stimulating these cells in culture, then injecting them in or injecting their exosome/vesicles into various joints to see if they get repair or suppress osteoarthritis (mouse model). Seems somewhat promising for stimulating repair process or delaying some osteoarthritis effects. Still seems somewhat non-specific, but might help people showing slow normal recovery.

            OK, back to work...
            Does it tell us anything that they are putting this into his circulatory system rather than injecting into the site?
            Bud Adams told me the franchise he admired the most was the Kansas City Chiefs. Then he asked for more hookers and blow.

            Comment


            • Jimmie Graham - or your posts about him - are already costing me too much mental strain, and the season hasn't even started.
              "The Devine era is actually worse than you remember if you go back and look at it."

              KYPack

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              • If Graham is absolutely leveled by a LB this year, will the hit be called a 'Graham Cracker'?
                Who Knows? The Shadow knows!

                Comment


                • Originally posted by Fritz View Post
                  Jimmie Graham - or your posts about him - are already costing me too much mental strain, and the season hasn't even started.
                  I can recommend a stem cell treatment for your mental anguish.
                  "Never, never ever support a punk like mraynrand. Rather be as I am and feel real sympathy for his sickness." - Woodbuck

                  Comment


                  • Originally posted by The Shadow View Post
                    If Graham is absolutely leveled by a LB this year, will the hit be called a 'Graham Cracker'?
                    S'mores is it's a black guy who leveled him.
                    One time Lombardi was disgusted with the team in practice and told them they were going to have to start with the basics. He held up a ball and said: "This is a football." McGee immediately called out, "Stop, coach, you're going too fast," and that gave everyone a laugh.
                    John Maxymuk, Packers By The Numbers

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                    • Originally posted by The Shadow View Post
                      If Graham is absolutely leveled by a LB this year, will the hit be called a 'Graham Cracker'?
                      Only if the LB is a GNA from south of the Mason/Dixon line.
                      I can't run no more with that lawless crowd
                      While the killers in high places say their prayers out loud
                      But they've summoned, they've summoned up a thundercloud
                      They're going to hear from me - Leonard Cohen

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                      • Originally posted by Joemailman View Post
                        Only if the LB is a GNA from south of the Mason/Dixon line.
                        GNA = Gawddamn Nazi Asshole?

                        Comment


                        • Originally posted by mraynrand View Post
                          Some mesenchymal stem cells or their vesicles can produce factors that in duce chondrocyte markers (possibly help repair) and suppress the expression of things that break down (or remodel) cartilage, as well as suppress inflammation and protect the resident cells that normally effect repairs from cellular death. I saw some osteoarthritis models that showed some promising results. I did see that they treated the cells with TGF beta - that kind of direct therapy has been under investigation for a while. So they are stimulating these cells in culture, then injecting them in or injecting their exosome/vesicles into various joints to see if they get repair or suppress osteoarthritis (mouse model). Seems somewhat promising for stimulating repair process or delaying some osteoarthritis effects. Still seems somewhat non-specific, but might help people showing slow normal recovery.

                          OK, back to work...
                          Now translate the above post into English. Not all of us are fluent in French Canadian.

                          Comment


                          • Originally posted by Anti-Polar Bear View Post
                            Now translate the above post into English. Not all of us are fluent in French Canadian.
                            ton corps te déteste
                            "Never, never ever support a punk like mraynrand. Rather be as I am and feel real sympathy for his sickness." - Woodbuck

                            Comment


                            • Originally posted by pbmax View Post
                              So if he was on a anti-inflammation protocol and it worked, then the vesicles contributed what exactly?
                              1) Was he? I didn't see that, but I assume he probably was. 2) Most protocols don't work that well. 3) Would you admit that HgH would have healed him? 4) If HgH is made by the body and heals, but we need a little extra for some things as we age, why not EVs??

                              I'm not sure this is the real deal either. I haven't studied this one and its relatively new. I'm simply saying that using what the good lord put in our bodies to heal it when triggered correctly is changing medicine and this COULD be the case with EVs.
                              The only time success comes before work is in the dictionary -- Vince Lombardi

                              Comment


                              • Originally posted by pbmax View Post
                                Does it tell us anything that they are putting this into his circulatory system rather than injecting into the site?
                                There is only minimal difference with many substances. If its in your circulatory system it will find its way to the site.
                                The only time success comes before work is in the dictionary -- Vince Lombardi

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